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"Gamechanger": FDA panel unanimously endorses Johnson & Johnson vaccine, clearing way for final approval

Added 02-26-21 06:35:02pm EST - “"It clearly gets way over the bar."” - Hotair.com

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Posted By TheNewsCommenter: From Hotair.com: “"Gamechanger": FDA panel unanimously endorses Johnson & Johnson vaccine, clearing way for final approval”. Below is an excerpt from the article.

Come Monday morning, millions of doses of a third vaccine should be rolling out across America. So far, over a span of more than two months, some 22 million people have gotten both doses of either Pfizer or Moderna. If Johnson & Johnson’s estimate that it can deliver 20 million doses in March proves correct, it’ll mean that J&J — a one-shot vaccine — could singlehandedly double the number of fully vaccinated Americans in the span of just a month.

Based on the totality of scientific evidence available, do the benefits of the J&J #covid19 vaccine outweigh its risks for people 18+?

J&J uses a different technology than the mRNA vaccines, Pfizer and Moderna. Those two send RNA to your cells instructing them to make the virus’s signature spike protein, which your immune system then detects and produces antibodies to combat. J&J is more of an old-fashioned vaccine. They repurpose a common cold virus by neutralizing it and implanting in it the gene for the spike protein; the virus is eventually absorbed by some of your cells and the gene is released into the cell nucleus. The nucleus then converts the DNA in the gene into RNA instructions to produce the spike protein, which again ends up triggering your immune system.

The efficacy data about the J&J vaccine is well known to people who follow COVID news. It was 72 percent effective overall in preventing infection, 85 percent effective in preventing “severe” cases of the disease, and 100 percent effective in preventing hospitalizations and deaths in clinical trials. The most salient fact about it right now is that it’s not quite as protective as the mRNA vaccines are against infection. Except … do we know for a fact that that’s true? Pfizer and Moderna were 95 percent effective against infection, but they were tested at a different phase of the pandemic. What if the reason J&J is “less effective” is because it was pitted in trials against a more formidable enemy than the mRNA vaccines had to cope with?

Some experts fear that lower [efficacy] number could feed public perceptions that J&J’s shot is a “second-tier vaccine.” But the difference in protection reflects when and where J&J conducted its studies.

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